Ibanga le-GMP i-Atosiban acetate yomjovo
| Igama elijwayelekile: | I-Atosiban Acetate |
| Inombolo yeCas: | 914453-95-5 |
| I-Molecular Formula: | I-C45H71N11O14S2 |
| Isisindo samangqamuzana: | 1054.25 g/mol |
| Ukulandelana: | Mpr-D-Tyr(OEt)-Ile-Thr-Asn-Cys-Pro-Orn-Gly-NH2 |
| Ukubukeka: | Impushana emhlophe exegayo |
| Isicelo: | I-Atosiban iyi-peptide yokwenziwa esebenza njenge-oxytocin receptor antagonist. Isetshenziswa ngokuyinhloko ku-obstetrics kanye ne-gynecology ukucindezela ukufinyela ngaphambi kwesikhathi kwesibeletho, okungaholela ekuzalweni ngaphambi kwesikhathi. Ngokuvimbela ukusebenza kwe-oxytocin, ihomoni enesibopho sokuvuselela ukufinyela kwesibeletho, i-Atosiban isiza ukubambezela ukuqala kokusikwa futhi andise isikhathi sokukhulelwa. Lo muthi ngokuvamile unikezwa ngomthambo futhi uvame ukusetshenziswa ekukhulelweni okusengozini enkulu lapho ukuzalwa ngaphambi kwesikhathi kuwukukhathazeka. Kuzuzisa kakhulu ezimeni lapho iminyaka yokukhulelwa iphakathi kwamaviki angama-24 kuya kwangu-33. I-Atosiban yaziwa ngokunciphisa ngempumelelo ukuvama nokuqina kokufinyela, inikeze ithuba lokunye ukungenelela okufanele kusetshenziswe, njengokusebenzisa i-corticosteroids ukuthuthukisa ukuvuthwa kwamaphaphu engane. I-Atosiban ivamise ukubekezelelwa kahle, ibe nemiphumela engemihle embalwa. Nokho, kungase kubangele ukusabela okuncane okubi, okufana nekhanda elibuhlungu, isicanucanu, nokushaywa umoya. Ezimweni ezingavamile, kungaholela ezinkingeni ezinzima kakhulu, njengokungezwani komzimba noma imiphumela yenhliziyo. Ngakho-ke, kubalulekile ukuthi ochwepheshe bezokunakekelwa kwempilo baqaphe eduze iziguli ezithola i-Atosiban. Sekukonke, i-Atosiban idlala indima ebalulekile ekuphathweni kwemisebenzi yangaphambi kwesikhathi, isiza ukuthuthukisa imiphumela yezingane ezisanda kuzalwa ngokuvumela isikhathi eside sokukhulelwa. Kuyithuluzi elibalulekile emkhakheni wezokubelethisa, elisiza ekuvimbeleni ukuzalwa ngaphambi kwesikhathi futhi linikeze izingane ithuba elingcono ekuqaleni okunempilo ekuphileni. |
| Iphakheji: | isikhwama se-aluminium foil noma i-aluminium TIN noma ngokwezidingo zekhasimende ngalinye |
| 1 | Umhlinzeki oqeqeshiwe wama-API we-peptide ovela e-China. |
| 2 | Imigqa yokukhiqiza engu-16 enamandla okukhiqiza amakhulu anenani elincintisanayo |
| 3 | I-DMF iyatholakala nemibhalo ethembekile. |
A: Yebo, singapakisha njengemfuneko yakho.
A: I-LC sight kanye ne-TT esikhathini sokukhokha kusengaphambili esikhethwayo.
IMP: Yebo, sicela unikeze ukucaciswa kwekhwalithi yakho, sizohlola i-R&D yethu futhi sizame ukufanisa ukucaciswa kwekhwalithi yakho.
