Ikhwalithi ephezulu ye-Cagrilintide API Powder
| Igama elijwayelekile: | I-Cagrilintide |
| Inombolo yeCas: | 1415456-99-3 |
| I-Molecular Formula: | I-C194H312N54O59S2 |
| Isisindo samangqamuzana: | 4109 g/mol |
| Ukubukeka: | Impushana emhlophe |
| Isicelo: | I-Cagrilintide iyisidakamizwa esisetshenziselwa ukwelapha isifo sikashukela sohlobo 2. Kuyi-peptide yokwenziwa esebenza njenge-agonist ku-glucagon-like peptide-1 (GLP-1) receptor. I-GLP-1 iyi-hormone ekhiqizwa emathunjini esiza ukulawula amazinga kashukela egazini. I-Caglilin peptide isebenza ngokuvuselela i-GLP-1 receptor, okuholela ekwandeni kokukhiqizwa kwe-insulin, ukwehla kokukhiqizwa kwe-glucagon, nokukhipha kancane kwesisu. Lokhu ekugcineni kusiza ukulawula amazinga kashukela egazini kubantu abanesifo sikashukela sohlobo lwe-2. Ngaphandle kwemiphumela yayo ekukhiqizweni kwe-insulin ne-glucagon, i-caglilintide ineminye imiphumela enenzuzo ekwelapheni uhlobo lwesifo sikashukela sohlobo 2. Kuye kwatholakala ukukhuthaza umuzwa wokugcwala, okuholela ekunciphiseni ukudla nokuncipha kwesisindo kwezinye iziguli. Lokhu kubalulekile ngoba ukuncipha kwesisindo kuhlotshaniswa nokulawulwa okuthuthukisiwe kwe-glycemic kanye nengozi encishisiwe yezinkinga zenhliziyo nemithambo yegazi kubantu abanesifo sikashukela sohlobo 2. Ukwengeza, i-canagrelin tide iboniswe ukuthi inezinzuzo zenhliziyo. Kutholwe ukuthuthukisa ukusebenza kwenhliziyo nokunciphisa ukuvuvukala ohlelweni lwenhliziyo, inkinga evamile kubantu abanesifo sikashukela. Lokhu kwenza kube inketho ebalulekile ezigulini ezinesifo sikashukela kanye nesifo senhliziyo. I-Canagrelin ivamise ukujova ngaphansi kwesikhumba kanye noma kabili ngosuku. Kubalulekile ukuthi iziguli zithole imfundo efanele kanye nesiqondiso sokuthi ungazinikeza kanjani imithi ukuze kuqinisekiswe ukusetshenziswa okuphumelelayo nokuphephile. Njenganoma yimuphi umuthi, i-caglilintide inemiphumela emibi engaba khona. Imiphumela emibi evame kakhulu ihlanganisa isicanucanu, ukuhlanza kanye nesifo sohudo. Le miphumela emibi ivamise ukuba ngcono ngokuhamba kwesikhathi njengoba umzimba ujwayela umuthi. I-Canagrelin ingase futhi yandise ubungozi be-hypoglycemia, ikakhulukazi uma isetshenziswa namanye ama-antidiabetic agents. Ukuqapha njalo amazinga kashukela egazini kuyadingeka ukuvimbela nokulawula i-hypoglycemia. Sekukonke, i-caglilin tide iyisengezo esibalulekile ekukhetheni ukwelashwa kweziguli ezinesifo sikashukela sohlobo 2. Kuyasiza ukulawula amazinga kashukela egazini, kukhuthaze ukuncipha, futhi kunezinzuzo zenhliziyo nemithambo yegazi. Kodwa-ke, kubalulekile ukuthi iziguli zisebenze eduze nomhlinzeki wazo wokunakekelwa kwezempilo ukuze zinqume ukuthi i-canagrelintide iyisinqumo esizilungele yini futhi ziqinisekise ukuthi umuthi usetshenziswa ngokuphepha nangempumelelo. |
| Iphakheji: | isikhwama se-aluminium foil noma i-aluminium TIN noma ngokwezidingo zekhasimende ngalinye |
| 1 | Umhlinzeki oqeqeshiwe wama-API we-peptide ovela e-China. |
| 2 | Imigqa yokukhiqiza engu-16 enamandla okukhiqiza amakhulu anenani elincintisanayo |
| 3 | Umkhiqizo ukhiqizwa e-US FDA kanye nesayithi eligunyaziwe le-EDQM. |
A: Yebo, singapakisha njengemfuneko yakho.
A: I-LC sight kanye ne-TT esikhathini sokukhokha kusengaphambili esikhethwayo.
IMP: Yebo, sicela unikeze ukucaciswa kwekhwalithi yakho, sizohlola i-R&D yethu futhi sizame ukufanisa ukucaciswa kwekhwalithi yakho.
Bhala umyalezo wakho lapha futhi usithumelele wona
