GMP grade Cagrilintide API for Umjovo
| Igama elijwayelekile: | I-Cagrilintide |
| Inombolo yeCas: | 1415456-99-3 |
| I-Molecular Formula: | I-C194H312N54O59S2 |
| Isisindo samangqamuzana: | 4109 g/mol |
| Ukubukeka: | Impushana emhlophe |
| Isicelo: | I-Cagrilintide iyisidakamizwa esisetshenziselwa ukwelapha isifo sikashukela sohlobo 2.Kuyi-peptide yokwenziwa esebenza njenge-agonist ku-glucagon-like peptide-1 (GLP-1) receptor.I-GLP-1 iyi-hormone ekhiqizwa emathunjini esiza ukulawula amazinga kashukela egazini.I-Caglilin peptide isebenza ngokuvuselela i-GLP-1 receptor, okuholela ekwandeni kokukhiqizwa kwe-insulin, ukwehla kokukhiqizwa kwe-glucagon, nokukhipha kancane kwesisu.Lokhu ekugcineni kusiza ukulawula amazinga kashukela egazini kubantu abanesifo sikashukela sohlobo lwe-2. Ngaphandle kwemiphumela yayo ku-insulin ne-glucagon secretion, i-caglilintide ineminye imiphumela enenzuzo ekwelapheni uhlobo lwesifo sikashukela sohlobo 2.Kuye kwatholakala ukukhuthaza umuzwa wokugcwala, okuholela ekunciphiseni ukudla nokuncipha kwesisindo kwezinye iziguli.Lokhu kubalulekile ngoba ukuncipha kwesisindo kuhlotshaniswa nokulawulwa okuthuthukisiwe kwe-glycemic kanye nengozi encishisiwe yezinkinga zenhliziyo nemithambo yegazi kubantu abanesifo sikashukela sohlobo 2.Ukwengeza, i-canagrelin tide iboniswe ukuthi inezinzuzo zenhliziyo.Kutholwe ukuthuthukisa ukusebenza kwenhliziyo nokunciphisa ukuvuvukala ohlelweni lwenhliziyo, inkinga evamile kubantu abanesifo sikashukela.Lokhu kwenza kube inketho ebalulekile ezigulini ezinesifo sikashukela kanye nesifo senhliziyo.I-Canagrelin ivamise ukujova ngaphansi kwesikhumba kanye noma kabili ngosuku.Kubalulekile ukuthi iziguli zithole imfundo efanele kanye nesiqondiso sokuthi ungazinikeza kanjani imithi ukuze kuqinisekiswe ukusetshenziswa okuphumelelayo nokuphephile.Njenganoma yimuphi umuthi, i-caglilintide inemiphumela emibi engaba khona.Imiphumela emibi evame kakhulu ihlanganisa isicanucanu, ukuhlanza kanye nesifo sohudo.Le miphumela emibi ivamise ukuba ngcono ngokuhamba kwesikhathi njengoba umzimba ujwayela umuthi.I-Canagrelin ingase futhi yandise ubungozi be-hypoglycemia, ikakhulukazi uma isetshenziswa namanye ama-antidiabetic agents.Ukuqapha njalo amazinga kashukela egazini kuyadingeka ukuvimbela nokulawula i-hypoglycemia.Sekukonke, i-caglilin tide iyisengezo esibalulekile ekukhetheni ukwelashwa kweziguli ezinesifo sikashukela sohlobo 2.Kuyasiza ukulawula amazinga kashukela egazini, kukhuthaze ukuncipha, futhi kunezinzuzo zenhliziyo nemithambo yegazi.Kodwa-ke, kubalulekile ukuthi iziguli zisebenze eduze nomhlinzeki wazo wokunakekelwa kwezempilo ukuze zinqume ukuthi i-canagrelintide iyisinqumo esizilungele yini futhi ziqinisekise ukuthi umuthi usetshenziswa ngokuphepha nangempumelelo. |
| Iphakheji: | isikhwama se-aluminium foil noma i-aluminium TIN noma ngokwezidingo zekhasimende ngalinye |
| 1 | Umhlinzeki oqeqeshiwe wama-API we-peptide ovela e-China. |
| 2 | Imigqa yokukhiqiza engu-16 enamandla okukhiqiza amakhulu anenani elincintisanayo |
| 3 | Umkhiqizo ukhiqizwa e-US FDA kanye nesayithi eligunyaziwe le-EDQM. |
A: Yebo, singapakisha njengemfuneko yakho.
A: I-LC sight kanye ne-TT esikhathini sokukhokha kusengaphambili esikhethwayo.
IMP: Yebo, sicela unikeze ukucaciswa kwekhwalithi yakho, sizohlola i-R&D yethu futhi sizame ukufanisa ukucaciswa kwekhwalithi yakho.
Bhala umyalezo wakho lapha futhi usithumelele wona
