Igama elijwayelekile: | I-Teripressin acetate |
Inombolo yeCas: | 14636-12-5 |
I-Molecular Formula: | I-C52H74N16O15S2 |
Isisindo samangqamuzana: | 1227.39 g/mol |
Ukulandelana: | I-H-Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2 acetate usawoti(Disulfide bond) |
Ukubukeka: | Impushana emhlophe |
Isicelo: | I-Terlipressin acetate iyi-analogue yokwenziwa ye-vasopressin esetshenziselwa ikakhulukazi ukwelapha izimo ezihlukahlukene, njengokuphuma kwegazi kwe-variceal esophageal, i-hepatorenal syndrome, kanye nokushaqeka kwe-septic. Kuyi-vasoconstrictor enamandla, okusho ukuthi isiza ukubopha imithambo yegazi futhi inyuse umfutho wegazi ezingxenyeni ezithile zomzimba. Lesi sidakamizwa, esivame ukunikezwa ngomjovo, sisebenza kuma-receptors athile emithanjeni yegazi ukunciphisa ukugeleza kwegazi ezindaweni lapho sidingeka khona, ngaleyo ndlela sinciphise ukopha noma sithuthukise umfutho wegazi. Ivamise ukusetshenziswa ezimeni eziphuthumayo, njengalapho isiguli sopha kakhulu ngenxa yokuguquguquka kommizo (imithambo yegazi enwetshiwe kummizo). Enye yezinzuzo eziyinhloko ze-tervasopressin acetate isikhathi eside sokusebenza kanye nekhono layo lokukhiqiza i-vasoconstriction eqhubekayo. Lokhu kusiza ukuzinzisa isimo sesiguli futhi kuthenga isikhathi sokungenelela okwengeziwe kwezokwelapha. Kodwa-ke, kubalulekile ukuqaphela ukuthi i-tervasopressin acetate iwumuthi kadokotela futhi kufanele usetshenziswe kuphela ngaphansi kokuqondisa nokuqondiswa uchwepheshe wezempilo. Njenganoma yisiphi isidakamizwa, singase sibe nemiphumela engemihle engaba khona, njengokuminca kwesisu, isicanucanu, noshintsho ekushayeni kwenhliziyo nomfutho wegazi. Ngakho-ke, kubalulekile ukuxoxa ngezingozi nezinzuzo zalo muthi nochwepheshe wezokwelapha oqeqeshiwe ngaphambi kokuqala ukwelashwa. Sengiphetha, i-tervasopressin acetate iwumuthi obalulekile wokwelapha izimo ezehlukene zezokwelapha ezihlobene nokopha nokulawulwa komfutho wegazi. Ikhono layo lokubopha imithambo yegazi lenza ithuluzi elibalulekile ezimeni eziphuthumayo lapho kudingeka khona isinyathelo esisheshayo. Noma kunjalo, ukugadwa okufanele kwezokwelapha kubalulekile ukuze kuqinisekiswe ukusetshenziswa kwayo okuphephile nempumelelo. |
Iphakheji: | isikhwama se-aluminium foil noma i-aluminium TIN noma ngokwezidingo zekhasimende ngalinye |
Amandla okukhiqiza: | 2 Kilogram/Inyanga |
1 | Umhlinzeki oqeqeshiwe wama-API we-peptide ovela e-China. |
2 | Imigqa yokukhiqiza engu-16 enamandla okukhiqiza amakhulu anenani elincintisanayo |
3 | I-GMP ne-DMF itholakala ngemibhalo enokwethenjelwa kakhulu. |
A: Yebo, singapakisha njengemfuneko yakho.
A: I-LC sight kanye ne-TT esikhathini sokukhokha kusengaphambili esikhethwayo.
IMP: Yebo, sicela unikeze ukucaciswa kwekhwalithi yakho, sizohlola i-R&D yethu futhi sizame ukufanisa ukucaciswa kwekhwalithi yakho.