I-Retatrutide, ukwelashwa okungaba khona kwesifo i-Alzheimer's, yenze inqubekelaphambili esivivinyweni sayo sakamuva somtholampilo, ebonisa imiphumela ethembisayo. Lezi zindaba ziletha ithemba ezigidini zeziguli nemindeni yazo ehlaselwe yilesi sifo esibhubhisayo emhlabeni jikelele. I-Retarglutide iwumuthi omusha owakhiwa inkampani ehamba phambili eyenza imithi eklanyelwe ngokuqondile ukukhomba umsuka wokugula kwesifo i-Alzheimer's. Iklanyelwe ukuphazamisa ukwakheka nokuqoqwa kwama-beta-amyloid plaques ebuchosheni, enye yezimpawu zesifo. Izivivinyo zemitholampilo zenziwa eminyakeni emibili edlule futhi zazibandakanya inani elikhulu leziguli ze-Alzheimer zamaqembu ahlukene obudala nezigaba zesifo. Imiphumela ibonise ukuthi i-retarglutide yehlisa kakhulu ukwehla kwengqondo kanye nokusebenza okuthuthukisiwe kwenkumbulo ezigulini ngesikhathi sokuhlolwa. UDkt Sarah Johnson, umcwaningi ohamba phambili walolu cwaningo, uzwakalise ukuba nethemba ngalokhu okutholwe. Uthe: "Imiphumela yethu yokuhlolwa komtholampilo ikhombisa ukuthi i-retarglutide inamandla okuguqula umdlalo ocwaningweni lwe-Alzheimer's. Ayigcinanga nje ngokubonisa ukusebenza okubalulekile ekubambezeleni ukuqhubeka kwesifo; ukuphepha." I-Retarglutide isebenza ngokubopha ku-amyloid beta, ivimbele ukuhlanganisa kwayo kanye nokwakheka kwama-plaque okulandelayo.
Le ndlela yokusebenza kulindeleke ukuthi ibe nomthelela omkhulu ekumiseni imiphumela ewohlokayo yesifo i-Alzheimer's kanye nokuvikela ukusebenza kwengqondo kweziguli. Nakuba le miphumela yocwaningo lwangaphambi kwesikhathi ikhuthaza ngempela, ukuhlolwa okwengeziwe kuyadingeka ukuze kutholwe ukusebenza kahle kwesikhathi eside, ukuphepha, kanye nemiphumela engemihle engaba khona ye-retalglutide. Inkampani eyenza imithi ihlela ukwethula izivivinyo ezinkulu ezibandakanya isibalo seziguli esihluke kakhulu ezinyangeni ezizayo. Isifo i-Alzheimer's yisifo se-neurodegenerative esithinta cishe abantu abayizigidi ezingama-50 emhlabeni jikelele. Kuhlotshaniswa nokwehla okuqhubekayo kwenkumbulo, ukucabanga, nokuziphatha, ekugcineni kuholele ekuthembeleni ngokuphelele kwabanye ukuze benze imisebenzi yansuku zonke. Njengamanje, izinketho zokwelashwa ezitholakalayo zilinganiselwe, okwenza ukutholakala kwama-ejenti okwelapha asebenzayo kubaluleke nakakhulu. Uma i-retarglutide iphumelela ezigabeni zokugcina zokuhlolwa komtholampilo, inamandla okuguqula ukuphathwa nokwelashwa kwesifo i-Alzheimer's. Iziguli nemikhaya yazo ekugcineni zingase zibone ukukhanya kwethemba njengoba zilwa nalesi sifo esibhubhisayo. Nakuba umgwaqo we-retarglutide oya ekuvunyweni kokulawula kanye nokusetshenziswa okusabalele kusengaba mude, le miphumela yakamuva yocwaningo lomtholampilo ikhuthaza ithemba nokuzimisela okuvuselelwe emiphakathini yesayensi nezokwelapha. Ucwaningo oluqhubekayo oluzungeze lo muthi lunikeza inhlansi yethemba lekusasa elingcono ezigidini zabantu abaphila nesifo i-Alzheimer's. Umshwana wokuzihlangula: Lesi sihloko sisekelwe emiphumeleni yokuqala yokuhlolwa komtholampilo futhi akufanele ithathwe njengeseluleko sezokwelapha. Kunconywa ukuthi uxhumane nochwepheshe bezokunakekelwa kwezempilo ukuze uthole ukuqondiswa komuntu siqu mayelana nesifo se-Alzheimer kanye nezinketho zokwelapha.
Isikhathi sokuthumela: Nov-01-2023